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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP9
All Species:
8.18
Human Site:
T107
Identified Species:
15
UniProt:
P55211
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55211
NP_001220.2
416
46281
T107
K
P
T
L
E
N
L
T
P
V
V
L
R
P
E
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
Rhesus Macaque
Macaca mulatta
XP_001082859
416
46192
T107
K
P
T
L
E
N
L
T
P
V
V
L
R
P
E
Dog
Lupus familis
XP_865164
414
45235
P107
L
T
P
G
K
L
A
P
V
V
L
G
P
A
E
Cat
Felis silvestris
Mouse
Mus musculus
P29594
452
50642
Y136
L
P
P
L
S
C
D
Y
D
T
S
L
P
F
S
Rat
Rattus norvegicus
P55215
452
50709
Y136
L
P
P
L
S
C
D
Y
D
S
S
L
P
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520982
366
40213
K84
V
P
V
P
S
T
T
K
R
E
Q
E
A
T
R
Chicken
Gallus gallus
Q98943
424
47941
Y111
I
A
T
L
E
Q
R
Y
G
S
N
L
P
L
P
Frog
Xenopus laevis
P55866
282
32106
V8
M
E
E
S
Q
N
G
V
K
Y
G
G
D
A
T
Zebra Danio
Brachydanio rerio
NP_001007405
436
48445
P105
V
I
S
V
Q
P
S
P
I
P
L
P
V
Q
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02002
323
35908
A47
E
S
L
V
V
G
G
A
T
A
A
S
P
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
M106
A
V
E
F
E
C
P
M
S
P
A
S
H
R
R
Sea Urchin
Strong. purpuratus
XP_799258
437
48470
T105
Q
M
G
Q
T
Q
A
T
T
P
H
D
N
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
93.9
76.9
N.A.
28.9
28.3
N.A.
52.8
31.1
22.6
47.2
N.A.
22.1
N.A.
21.6
32.2
Protein Similarity:
100
35.8
96.8
84.1
N.A.
46.9
46.2
N.A.
65.6
48.3
38.7
64.2
N.A.
35.8
N.A.
37.5
51
P-Site Identity:
100
0
100
13.3
N.A.
20
20
N.A.
6.6
26.6
6.6
0
N.A.
0
N.A.
6.6
6.6
P-Site Similarity:
100
0
100
26.6
N.A.
20
20
N.A.
6.6
26.6
13.3
26.6
N.A.
13.3
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
16
8
0
8
16
0
8
16
0
% A
% Cys:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
16
0
16
0
0
8
8
0
0
% D
% Glu:
8
8
16
0
31
0
0
0
0
8
0
8
0
0
24
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
16
0
% F
% Gly:
0
0
8
8
0
8
16
0
8
0
8
16
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
16
0
0
0
8
0
0
8
8
0
0
0
0
0
0
% K
% Leu:
24
0
8
39
0
8
16
0
0
0
16
39
0
16
0
% L
% Met:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
24
0
0
0
0
8
0
8
0
8
% N
% Pro:
0
39
24
8
0
8
8
16
16
24
0
8
39
16
24
% P
% Gln:
8
0
0
8
16
16
0
0
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
8
0
8
0
0
0
16
16
16
% R
% Ser:
0
8
8
8
24
0
8
0
8
16
16
16
0
0
16
% S
% Thr:
0
8
24
0
8
8
8
24
16
8
0
0
0
8
8
% T
% Val:
16
8
8
16
8
0
0
8
8
24
16
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
24
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _